Typology – Technological innovation: The 100% vegan micro-spicula serum A63

Inspired by aesthetic medicine, this product is the first 100% vegan micro-spicule serum made in France.

The A63 Regenerating Micro-Spicule Serum replaces traditional animal-derived active ingredients—such as those from sea sponges and fish DNA—with ethical, purely mineral, and biotechnological innovations.

Mélanie Klein – Bioengineer & Product Manager at Typology

„Our challenge in developing the A63 Regenerating Micro-Spicule Serum was to offer an at-home treatment inspired by aesthetic medicine without compromising our ethical and environmental commitments. While the market continues to rely on animal-derived active ingredients, we are innovating with vegan micro-spicules of mineral origin and a biotechnologically derived vegan PDRN.

Our precise dosage of 150,000 micro-spicules per gram of product strikes the perfect balance between a slight tingling sensation—signaling the product’s activation—and controlled skin tolerance. These micro-spicules create superficial micro-channels on the skin’s surface. They allow our EGF and PDRN active ingredient complex—molecules normally too large to penetrate the skin barrier—to reach deeper into the epidermis for maximum efficacy. All this within a minimalist, highly natural formula with clinically proven results.“

The Formula in Detail

100% plant-based and mineral alternatives have been developed to replace animal-derived active ingredients:

The Spicule Alternative – from sea sponges to pure minerals: Conventional serums use microscopic needles derived from sea sponges. Instead, the Regenerating Micro-Spicule Serum A63 utilizes microneedles of 100% mineral origin—with 150,000 needles per gram. These create ultra-fine micro-channels in the skin’s uppermost layer, acting as a delivery system. This allows larger „better-aging“ molecules to penetrate the skin barrier while simultaneously stimulating natural cell renewal.

The PDRN Alternative – from salmon DNA to probiotic fermentation: PDRN is known for its healing and collagen-boosting properties but is traditionally derived from fish DNA. A 100% vegan PDRN was created through the fermentation of the specific probiotic strain *Lactobacillus rhamnosus*. It leaves the skin feeling comfortable, reduces inflammation, and strengthens the skin structure—all without impacting marine life.

Application: Apply the serum 1–2 times a week; use exclusively in the evening.